NHTSA & EPA data · updated November 2, 2026

2021 Ford E-350 recalls, problems & safety ratings

Quick answer

NHTSA lists 6 recalls for the 2021 Ford E-350 and 22 owner complaints. The most-reported problem areas are engine (11), steering (7), service brakes (7).

The 2021 has the most owner complaints of any E-350 model year from 2012 to 2026. It has 6 recalls vs. an average of 4.9 per model year.

Free. Shows whether a recall applies, plus specs, problems and ratings for your exact vehicle.

Recalls 6

Every recall NHTSA lists for the 2021 Ford E-350. Not every recall applies to every vehicle, so check your VIN. Recall repairs are free at a franchised dealer.

EngineNHTSA #25V793000 · 11/17/2025

Problem: Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles that received an incomplete software update under recall 20V795. The engine cover may become excessively hot.

Risk: Direct contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.

Fix: Dealers will update the powertrain calibration for heat management under elevated idle conditions, free of charge. Owner notification letters were mailed January 7, 2026. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 25SC7. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning December 22, 2025.

Steering · hydraulic power assist · hose, piping, and connectionsNHTSA #24V097000 · 02/09/2024

Problem: Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake hydroboost unit may result in a sudden loss of power steering fluid.

Risk: A sudden loss of power steering fluid can result in a loss of power steering and power brake assist, increasing the risk of a crash.

Fix: Dealers will replace the power steering pressure line and the hydroboost jumper line, free of charge. Vehicles in this recall were previously recalled under 22V-089 and owners will need to have the new remedy completed even if their vehicle was remedied under the prior recall. Owner notification letters were mailed on June 21, 2024. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 24S07.

Steering · hydraulic power assist · hose, piping, and connectionsNHTSA #22V089000 · 02/16/2022

Problem: Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake Hydroboost unit may result in a sudden loss of power steering fluid.

Risk: A sudden loss of power steering fluid can result in a loss of power steering and power brake assist, increasing the risk of a crash.

Fix: Dealers will inspect the connection between the power steering lines and the Hydroboost unit, and replace the power steering lines, as necessary, free of charge. Owner notification letters were mailed on March 18, 2022. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 22S08.

EngineNHTSA #20V795000 · 12/17/2020

Problem: Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. The underside of the engine cover may have mispositioned insulation, allowing the cover to get excessively hot.

Risk: Direct and continuous contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.

Fix: Ford will notify owners, and dealers will inspect the engine cover for gaps between the rubber seal and the insulation. If gaps are present, the dealer will install engine cover insulation patches in the right hand and left hand inner lower corners of the engine cover. The dealer will also update the powertrain calibration for heat management under elevated idle conditions should a vehicle be equipped with SEIC or BCP, free of charge. The recall began February 15, 2021. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S73.

Service brakes, hydraulic · antilock/traction control/electronic limited slipNHTSA #20V175000 · 03/23/2020

Problem: Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. A wire harness in the rear of the vehicle may contact the vehicle frame, resulting in damage to the circuits that support the fuel pump and the anti-lock braking system (ABS).

Risk: Damage to the fuel pump circuit in the wiring harness could result in an unexpected engine stall. Damage to the ABS wiring can lead to reduction of ABS functionality and a loss of roll stability control (RSC) functionality. These scenarios increase the risk of a crash.

Fix: Ford will notify owners, and dealers will inspect the wire harness for damage. If no damage is found, dealers will apply anti-abrasion tape over the area and ensure clearance to surrounding components. If damage is found, dealers will splice in new wire and apply anti-abrasion tape over the area and ensure clearance to surrounding components. All services will be performed free of charge. The recall began May 18, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S13.

Power train · driveline · differential unitNHTSA #20V099000 · 02/21/2020

Problem: Ford Motor Company (Ford) is recalling certain 2020 F-550 and 2021 E-350 and E-450 vehicles. The rear axle differential fluid may be below the minimum level, possibly resulting in a failure of the rear axle assembly and driveshaft separation.

Risk: If the driveshaft separates, there may be a loss of drive, increasing the risk of crash. Additionally, if the parking brake is not applied, unintended vehicle movement can occur and increase the risk of injury or crash.

Fix: Ford will notify owners, and dealers will inspect the rear axle differential fluid level and adjust it, or replace the rear axle as necessary, free of charge. The recall began March 19, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S09.

Common problems

From complaints owners filed with NHTSA. Complaints aren't verified, but patterns across hundreds of owners point to known weak spots.

Most-reported problem areas

Engine11
Steering7
Service brakes7
Hydraulic5
Unknown or other2
Fuel system1
Diesel1
Traction control system1

By the numbers

22owner complaints filed
1involved a crash
0involved a fire
0injuries reported

Recent owner reports

09/13/2026 · Engine

Engine failure on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was taken out of service and has not run since. Two diagnoses, both in writing. ACME Mobile Service, July 27, 2026, at 152,760 miles: "Found the #5 cylinder is completely disabled and dropped out. Truck will need a new motor." Ford of Spartanburg (Ford dealership), Repair Order 595835, A…

09/13/2026 · Engine

Engine misfire on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was delivered to Ford of Spartanburg (Ford dealership) for diagnosis. The vehicle is still out of service. Ford's diagnosis, Repair Order 593079, June 26, 2026: "WILL NEED TO REPLACE ALL SPARK PLUGS AND WIRES, WILL ALSO NEED TO REPLACED ALL COILS DUE TO MISFIRES ON ALMOST EVERY CYLINDER.…

01/31/2026 · Engine

fatal Camshaft and lifter failure requiring an engine replacement

Safety ratings

NHTSA hasn't published 5-star crash ratings for the 2021 Ford E-350.

Fuel economy

The EPA doesn't publish fuel economy ratings for heavy-duty pickups like the Ford E-350.

Other model years

Compare every Ford E-350 year

Questions

How many recalls does the 2021 Ford E-350 have?

NHTSA lists 6 recalls for the 2021 Ford E-350, most recently for engine (11/17/2025). Recall repairs are free at a franchised dealer. Enter your VIN to check whether a recall applies to your vehicle.

What are the most common problems with the 2021 Ford E-350?

Based on 22 owner complaints filed with NHTSA, the most-reported areas are engine (11), steering (7), service brakes (7).

Is the 2021 Ford E-350 safe?

NHTSA hasn't published an overall 5-star rating for the 2021 Ford E-350.

Is the 2021 a good year for the Ford E-350?

The 2021 has the most owner complaints of any E-350 model year from 2012 to 2026. It has 6 recalls vs. an average of 4.9 per model year.

Own a 2021 Ford E-350 in South Carolina?

Our mobile mechanics diagnose and fix the problems above at your home, office or fleet lot in Lexington, Columbia and the Midlands, with dealer-grade scan tools.

Related vehicles

Sources: NHTSA recalls, complaints and 5-Star Safety Ratings APIs; EPA fueleconomy.gov. Data retrieved November 2, 2026. NHTSA model names used: E-350, ECONOLINE.

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